drugset / Trial / NCT00704496

The Effect of Pseudoephedrine on Rhinitis and Sleep

NCT00704496

Phase 3 Completed 34 enrolled Milton S. Hershey Medical Center
RandomizedCrossoverDouble-blindTreatment

Summary

The hypothesis is that pseudoephedrine, a sympathomimetic amine commonly used as a decongestant, will decrease nasal congestion leading to increased patency of the nose and a decrease in nighttime sleep fragmentation in individuals with year round perennial allergic rhinitis (PAR). This decrease in sleep fragmentation will reduce daytime somnolence and fatigue.

Timeline

Start
2007-06
Primary completion
2009-09
Completion
2009-09

Drugs

EvaluationDrugModalityDoseRoute
Comparator Pseudoephedrine Small molecule 240 mg Oral