drugset / Trial / NCT00704496
The Effect of Pseudoephedrine on Rhinitis and Sleep
RandomizedCrossoverDouble-blindTreatment
Summary
The hypothesis is that pseudoephedrine, a sympathomimetic amine commonly used as a decongestant, will decrease nasal congestion leading to increased patency of the nose and a decrease in nighttime sleep fragmentation in individuals with year round perennial allergic rhinitis (PAR). This decrease in sleep fragmentation will reduce daytime somnolence and fatigue.
Timeline
- Start
- 2007-06
- Primary completion
- 2009-09
- Completion
- 2009-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Pseudoephedrine | Small molecule | 240 mg | Oral |