drugset / Trial / NCT00705341
MethaCholine Bronchoprovocation Study (MeCIS)
Phase 4
Completed
219 enrolled
Johns Hopkins Bloomberg School of Public Health
Baylor College of Medicine · collabDuke University · collabIndiana University · collabLong Island Jewish Medical Center · collabLouisiana State University Health Sciences Center in New Orleans · collabNYU Langone Health · collabNational Jewish Health · collabNemours Children's Clinic · collabNorth Shore University Hospital · collabNorthwestern University · collabOhio State University · collabSt. Louis University · collabUniversity of California, San Diego · collabUniversity of Florida · collabUniversity of Miami · collabUniversity of Missouri-Columbia · collabUniversity of South Florida · collabUniversity of Vermont · collabWashington University School of Medicine · collab
RandomizedCrossoverQuadruple-blindDiagnostic
Summary
The purpose of this research is to evaluate the methacholine challenge test as an accurate indicator of asthma in patients receiving treatment for asthma. Phase 1 on the study compares methacholine challenge test results from asthma patients to those from people who do not have asthma. In phase 2, test results for people with asthma on low dose inhaled corticosteroid will be compared to results on high dose inhaled corticosteroids. Both males and females with stable asthma (asthma participants) and without asthma (controls) enrolled. Participants will be between 12 and 69 years of age.
Timeline
- Start
- 2009-01
- Primary completion
- 2010-02
- Completion
- 2010-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Fluticasone | Other / unclassified | 250 ug | Inhaled |
| Comparator | Fluticasone | Other / unclassified | 1000 ug | Inhaled |