Phase I Study in China - Tolerability of a Single Dose of Abatacept 30 mg/kg

Summary

The purpose of this study is to determine whether abatacept at a dose 30 mg/kg via intravenous infusion is safe and well tolerated in the treatment of lupus nephritis in mainland Chinese subjects with systemic lupus erythematosus (SLE)

Timeline

Start

2008-08

Primary completion

2009-01

Completion

2011-07

Publications

• Background Liu MF, Wang CR, Lin LC, Wu CR. CTLA-4 gene polymorphism in promoter and exon-1 regions in Chinese patients with systemic lupus erythematosus. Lupus. 2001;10(9):647-9. doi: 10.1191/096120301682430249.

Drugs

Indications