drugset / Trial / NCT00707876

Magnetic Resonance Angiography for Peripheral Arterial Disease (PAD)

NCT00707876

Phase 2 Completed 119 enrolled AMAG Pharmaceuticals, Inc.
RandomizedFactorialOpen-labelDiagnostic

Summary

The purpose of this study is to compare the difference between two magnetic resonance imaging (MRI) techniques for visualizing arteries. The study hypothesizes that one method that relies upon imaging flowing blood in the pelvic and leg arteries will not be as accurate or efficient as injecting a safe imaging agent to change the appearance of the blood on the MRI. Both methods will be compared with Digital Subtraction Angiography (DSA).

Timeline

Start
2008-09-01
Primary completion
2010-07-02
Completion
2020-08-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Ferumoxytol Diagnostic / imaging agent 1 mg/kg Intravenous
Subject Ferumoxytol Diagnostic / imaging agent 2.5 mg/kg Intravenous
Subject Ferumoxytol Diagnostic / imaging agent 4 mg/kg Intravenous