drugset / Trial / NCT00709527

ARC1905 (Anti-C5 Aptamer) Given With Lucentis 0.5 mg In People With Neovascular Age-Related Macular Degeneration

NCT00709527

Phase 1 Completed 60 enrolled Ophthotech Corporation
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The objectives of this study are to evaluate the safety, tolerability, and pharmacokinetic profile of multiple doses of ARC1905 intravitreous injection when administered in combination with multiple doses of Lucentis® 0.5 mg/eye, or with one induction dose of Lucentis 0.5 mg/eye in subjects with subfoveal choroidal neovascularization secondary to age-related macular degeneration (AMD).

Timeline

Start
2008-10-16
Primary completion
2009-12-30
Completion
2009-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Avacincaptad Pegol Aptamer Intravitreal