drugset / Trial / NCT00713622
Comparing The Effect On Cognition Of Adjunctive Therapy With Zonisamide Versus Sodium Valproate
RandomizedParallel-groupOpen-labelTreatment
Summary
Zonisamide (Zonegran) and sodium valproate (Epilim) are both medicines approved to treat epilepsy. The purpose of this study is to find out the extent to which zonisamide may affect memory and concentration, compared to sodium valproate.
Timeline
- Start
- 2008-06
- Primary completion
- 2008-12
- Completion
- 2009-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Valproate | Small molecule | 100 mg | — |
| Comparator | Valproate | Small molecule | 200 mg | — |
| Comparator | Valproate | Small molecule | 500 mg | — |
| Comparator | Valproate | Small molecule | 600 mg | — |
| Comparator | Valproate | Small molecule | 2500 mg | — |
| Comparator | Zonisamide | Other / unclassified | 25 mg | — |
| Comparator | Zonisamide | Other / unclassified | 50 mg | — |
| Comparator | Zonisamide | Other / unclassified | 100 mg | — |