drugset / Trial / NCT00714779
Fluoxetine vs. Brief Psychotherapy for Major Depression
RandomizedParallel-groupOpen-labelTreatment
Summary
In this study we compare two treatments for major depression - fluoxetine and brief psychodynamic psychotherapy. In addition to more traditional outcome measures, we also measure the densities of 5HT-1A and D-2 receptors before and after the treatment. The main hypothesis is that brief psychotherapy is as effective as fluoxetine.
Timeline
- Start
- 2000-01
- Primary completion
- 2004-12
- Completion
- 2004-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Fluoxetine | Small molecule | 20 mg | Oral |
| Comparator | Fluoxetine | Small molecule | 40 mg | Oral |