drugset / Trial / NCT00716989

Pathophysiological Study of Characteristics of the Changes in the Cutaneous Immune System After Intradermal Antigen Injections

NCT00716989 ↗

Terminated 36 enrolled Hospices Civils de Lyon
Non-randomizedSingle-groupOpen-labelBasic science

Summary

The goal of the vaccination is to induce humoral (antibody) and intracellular (T lymphocyte) responses. Various data show that intradermal vaccination is more efficient than intramuscular vaccination: the humoral response is statistically better after intradermic vaccination, compared to intramuscular vaccination, even in target populations such as older subjects or immunosuppressed patients

Timeline

Start
2008-11
Primary completion
2009-09
Completion
2009-09

Outcome

Outcome not reported

Stopped: “Third group realisation has not been necessary regarding the results of the first two groups (no sufficient modifications in the immune response)”

Drugs

EvaluationDrugModalityDoseRoute
Subject Tuberculin antigen Unknown 0.05 ml Intrathecal