drugset / Trial / NCT00716989
Pathophysiological Study of Characteristics of the Changes in the Cutaneous Immune System After Intradermal Antigen Injections
Non-randomizedSingle-groupOpen-labelBasic science
Summary
The goal of the vaccination is to induce humoral (antibody) and intracellular (T lymphocyte) responses. Various data show that intradermal vaccination is more efficient than intramuscular vaccination: the humoral response is statistically better after intradermic vaccination, compared to intramuscular vaccination, even in target populations such as older subjects or immunosuppressed patients
Timeline
- Start
- 2008-11
- Primary completion
- 2009-09
- Completion
- 2009-09
Outcome
Outcome not reported
Stopped: “Third group realisation has not been necessary regarding the results of the first two groups (no sufficient modifications in the immune response)”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tuberculin antigen | Unknown | 0.05 ml | Intrathecal |