drugset / Trial / NCT00718523

Study of Adding AMG 479 to First Line Chemotherapy in Patients With Optimally Debulked Epithelial Ovarian Cancer

NCT00718523

Phase 2 Terminated 170 enrolled Translational Research in Oncology
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study will determine the value of adding AMG 479 (fully human monoclonal antibody against IGF-1R) to paclitaxel and carboplatin first line chemotherapy in patients with optimally debulked (\<1 cm) FIGO stage III and IV (positive pleural cytology only) ovarian epithelial (including fallopian tube and primary peritoneal) carcinoma.

Timeline

Start
2009-01
Primary completion
2013-09
Completion
2014-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Ganitumab Monoclonal antibody 18 mg/kg Other

Indications