drugset / Trial / NCT00721331
A Phase I Study to Assess the Safety and Tolerability of Topical CRx-197 Formulations in Healthy Volunteers
RandomizedFactorialTriple-blindTreatment
Summary
This will be a phase I, single center, randomized, vehicle-controlled, blinded study comparing two dosage strengths of CRx-197 cream, nortriptyline, an active comparator (0.1% mometasone) and placebo (the active ingredient free vehicle cream of CRx-197)in healthy volunteers.
Timeline
- Start
- 2008-07
- Primary completion
- 2008-09
- Completion
- 2008-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Loratadine | Small molecule | 0.1 % | Topical |
| Subject | Loratadine | Small molecule | 0.3 % | Topical |
| Comparator | Mometasone | Other / unclassified | 0.1 % | Topical |
| Subject | Nortriptyline | Small molecule | 0.1 % | Topical |