drugset / Trial / NCT00724009
Clofarabine Bone Marrow Cytoreduction
NaSingle-groupOpen-labelTreatment
Summary
For relapsed and refractory leukemia patients induction chemotherapy prior to initiating a conditioning regimen will decrease residual leukemia (as measured by bone marrow leukemia blast percentage) at the time of HCT. This should lead to reduced relapse while still maintaining low transplant related mortality.
Timeline
- Start
- 2007-12
- Primary completion
- 2010-09
- Completion
- 2012-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Clofarabine | Other / unclassified | 30 mg/m2 | Intravenous |