drugset / Trial / NCT00726180

Use of Trastuzumab to Induce Increased ER Expression in ER-negative/Low, Her-2/Neu Positive Breast Cancer

NCT00726180

Phase 1/2 Terminated 1 enrolled University of Michigan Rogel Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

The majority pf breast cancers present as ER-positive, many of which are able to be targeted with multiple hormonal therapies. Altering ER-negative tumors to increase ER expression has the potential to benefit patients by making hormonal therapies a therapeutic option and possibly improving their overall prognosis.

Timeline

Start
2008-07
Primary completion
2010-06
Completion
2010-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Trastuzumab Monoclonal antibody Intravenous

Indications