drugset / Trial / NCT00728013

China Intensive Lipid Lowering With Statins in Acute Coronary Syndrome

NCT00728013

RandomizedParallel-groupOpen-labelTreatment

Summary

In summary, the CHILLAS study will be the first multicenter study performed in a Chinese population using a patient-level analysis to compare the effects and safety of intensive statin therapy with that of moderate statin therapy. Therefore, it will determine whether "lower is better", that is, whether LDL cholesterol lowering to a level of approximately 100mg/dl provides a benefit inferior to that of LDL cholesterol lowering to a much lower level; examine the role of inflammatory markers in predicting cardiac events and response to statin therapy; and evaluate the effects of statin therapy on regression of coronary atherosclerosis using IVUS.

Timeline

Start
2006-12
Primary completion
2008-12
Completion
2010-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Atorvastatin Small molecule 10 mg
Subject Atorvastatin Small molecule 20 mg
Subject Atorvastatin Small molecule 40 mg