Study of Nasonex in the Relief of Nasal Congestion in Patients With Seasonal Allergic Rhinitis (Study P05583)

Phase 3 Completed 333 enrolled Organon and Co

RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study seeks to prospectively demonstrate that Nasonex is better than placebo in relieving nasal congestion in patients with seasonal allergic rhinitis.

Timeline

Start: 2008-08
Primary completion: 2008-10
Completion: 2008-10

Outcome

Met primary endpoint

registry analysis (unspecified test); Mometasone Furoate Nasal Spray vs Placebo Nasal Spray; p <0.001; Difference in LS Means -0.31 (95% CI -0.43 to -0.19); ANCOVA NCT00728416 ↗

paper the primary end point, was significantly (p < 0.001) greater with MFNS than with placebo PMID 21439168 ↗

Publications

Results Meltzer EO, Shekar T, Teper AA. Mometasone furoate nasal spray for moderate-to-severe nasal congestion in subjects with seasonal allergic rhinitis. Allergy Asthma Proc. 2011 Mar-Apr;32(2):159-67. doi: 10.2500/aap.2011.32.3424.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Mometasone furoate	Other / unclassified	200 ug	Other