drugset / Trial / NCT00728936

Placebo-controlled, Dose-escalation Study of the Safety of IMO-2125 (Immunomodulatory Oligonucleotide) in Hepatitis C-infected Patients

NCT00728936

Phase 1 Completed 58 enrolled Idera Pharmaceuticals, Inc.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

First-in-humans, phase 1, dose-escalation study with 4 dose levels of single-agent IMO-2125.

Timeline

Start
2007-09
Primary completion
2009-12
Completion
2010-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Tilsotolimod Unknown 0.04 mg/kg
Subject Tilsotolimod Unknown 0.08 mg/kg
Subject Tilsotolimod Unknown 0.16 mg/kg
Subject Tilsotolimod Unknown 0.32 mg/kg
Subject Tilsotolimod Unknown 0.48 mg/kg