drugset / Trial / NCT00729976

Oral Versus Rectal Ibuprofen for Fever in Young Children - a Randomized Control Study.

NCT00729976 ↗

Phase 4 Unknown 40 enrolled Assaf-Harofeh Medical Center
RandomizedParallel-groupOpen-labelTreatment

Summary

Fever is one of the most common symptoms in pediatrics and one of the most common reasons for visits in pediatricians' office and pediatric emergency departments. Many parents consider fever to be the most terrifying symptom. Ibuprofen is an effective and safe treatment for febrile children. Until recently ibuprofen was available only in tablets suspension and as a liquid gel. All these dosage form are administered orally. Rectal suppositories are often essential for treating febrile children who cannot take medications by mouth (e.g vomiting). In the current study we aim to compare the effect on fever of ibuprofen given as suspension with ibuprofen suppositories.

Timeline

Start
2008-09
Primary completion
2010-12
Completion
2011-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ibuprofen Small molecule 5 mg/kg Rectal
Comparator Ibuprofen Small molecule 10 mg/kg Rectal

Indications

No indication recorded.