Study of ChimeriVax™ Dengue Tetravalent Vaccine in Adult Subjects

Summary

To evaluate effect of previous flavivirus exposure on the safety and immunogenicity of the ChimeriVax™ dengue tetravalent vaccine Primary Objectives: * To describe the safety of one injection of ChimeriVax™ dengue tetravalent vaccine. * To describe the immune response against dengue before and after one injection of ChimeriVax™ dengue tetravalent vaccine

Timeline

Start

2006-08

Primary completion

2007-08

Completion

2008-01

Publications

• Results Qiao M, Shaw D, Forrat R, Wartel-Tram A, Lang J. Priming effect of dengue and yellow fever vaccination on the immunogenicity, infectivity, and safety of a tetravalent dengue vaccine in humans. Am J Trop Med Hyg. 2011 Oct;85(4):724-31. doi: 10.4269/ajtmh.2011.10-0436.

Drugs

Indications