drugset / Trial / NCT00731523

Pharmacokinetics (PK) and Metabolism of FTY720 in Patients With Severe Renal Impairment and Healthy Matched Subjects.

NCT00731523

Phase 1 Completed 18 enrolled Novartis
NaSingle-groupOpen-labelOther

Summary

The purpose of this study is to compare the pharmacokinetics of FTY720 and its metabolites in patients with severe renal insufficiency and in matched, healthy volunteers. This study will allow a better understanding of the effects of renal insufficiency on the disposition of FTY720.

Timeline

Start
2008-07
Primary completion
2008-08
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Fingolimod Small molecule