drugset / Trial / NCT00734240
Safety and Tolerability of Single and Multiple Doses of ISIS 353512 in Healthy Volunteers
RandomizedSingle-groupTriple-blindTreatment
Summary
The purpose of this study is to evaluate the safety and tolerability of single and multiple doses of ISIS 353512, to evaluate the blood concentration and rate elimination of ISIS 353512 from the blood, and to evaluate the effectiveness of ISIS 353512 in lowering a protein in the blood associated with inflammation.
Timeline
- Start
- 2008-07
- Primary completion
- 2010-02
- Completion
- 2010-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ISIS 353512 | Unknown | 50 mg | Intravenous |
| Subject | ISIS 353512 | Unknown | 100 mg | Intravenous |
| Subject | ISIS 353512 | Unknown | 200 mg | Intravenous |