Study of FlutiForm® Versus Fluticasone Plus Formoterol in Adult Subjects With Severe Asthma

Summary

The study compares the efficacy and safety of FlutiForm® vs Flixotide® plus Foradil® in the treatment of severe persisent asthma in adult subjects.

Timeline

Start

2008-09

Primary completion

2009-06

Completion

2009-10

Outcome

Met primary endpoint

paper primary outcome measure: there were similar increases in mean pre-morning dose forced expiratory volume in the first second (FEV(1)) PMID 21196104 ↗

Publications

• Dissanayake S, Jain M, Grothe B, McIver T, Papi A. An evaluation of comparative treatment effects with high and low dose fluticasone propionate/formoterol combination in asthma. Pulm Pharmacol Ther. 2015 Dec;35:19-27. doi: 10.1016/j.pupt.2015.10.001. Epub 2015 Nov 10.
• Bodzenta-Lukaszyk A, Pulka G, Dymek A, Bumbacea D, McIver T, Schwab B, Mansikka H. Efficacy and safety of fluticasone and formoterol in a single pressurized metered dose inhaler. Respir Med. 2011 May;105(5):674-82. doi: 10.1016/j.rmed.2010.11.011. Epub 2010 Dec 31.

Drugs

Indications