Trial Of AG-013736, Cisplatin, And Gemcitabine For Patients With Squamous Non-Small Cell Lung Cancer

Phase 2 Completed 38 enrolled Pfizer

NaSingle-groupOpen-labelTreatment

Summary

This study will evaluate whether AG-013736 when combined with cisplatin and gemcitabine shows activity and is safe in patients with squamous type of non-small cell lung cancer

Timeline

Start: 2008-12
Primary completion: 2011-11
Completion: 2011-11

Publications

Bondarenko IM, Ingrosso A, Bycott P, Kim S, Cebotaru CL. Phase II study of axitinib with doublet chemotherapy in patients with advanced squamous non-small-cell lung cancer. BMC Cancer. 2015 May 1;15:339. doi: 10.1186/s12885-015-1350-6.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Axitinib	Small molecule	5 mg	Oral
Background	Cisplatin	Other / unclassified	80 mg/m2	Intravenous
Background	Gemcitabine	Small molecule	1250 mg/m2	Intravenous

Trial Of AG-013736, Cisplatin, And Gemcitabine For Patients With Squamous Non-Small Cell Lung Cancer

Summary

Timeline

Publications

Drugs

Indications