Efficacy of Acyclovir in Combination With a Glucocorticosteroid on UV-Induced Herpes Labialis

Summary

The primary objective was to compare the efficacy of ME-609 cream vs placebo cream on the time to healing (loss of hard crust) of delayed classical herpes labialis (HSV) lesions experimentally induced after ultra violet radiation (UVR) exposure.

Timeline

Start

1999-08

Primary completion

2000-08

Completion

2000-08

Outcome

Missed primary endpoint

release “The results indicated that ME-609 cream reduced the healing time of cold sores by 15% compared to placebo (ITT, p=0.084 based on log transformed data).” medivir.com ↗

Drugs

Indications