drugset / Trial / NCT00736775

A Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Anti-Abeta (MABT5102A) in Patients With Alzheimer's Disease

NCT00736775 ↗

Phase 1 Completed 56 enrolled Genentech, Inc.
RandomizedParallel-groupDouble-blindTreatment

Summary

This is a Phase I, multicenter, randomized, double-blind, placebo-controlled study that will be conducted in the United States and consists of a single ascending-dose stage followed by a multidose, parallel-treatment stage. This study will be conducted in approximately 50 adult patients between 50-85 years old who have mild to moderate Alzheimer's disease.

Timeline

Start
2008-08
Primary completion
2010-05
Completion
—

Drugs

EvaluationDrugModalityDoseRoute
Subject Crenezumab Monoclonal antibody — Intravenous

Indications