drugset / Trial / NCT00741741

TMC278-TiDP15-C150: Trial to Examine Safety, Tolerability and Plasma Pharmacokinetics of Multiple Doses of TMC278LA.

NCT00741741

Phase 1 Terminated 20 enrolled Tibotec Pharmaceuticals, Ireland
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is: to determine the safety, (local) tolerability and plasma exposure over time of single intramuscular (IM) doses of 600 and 1200 mg of a new formulation (F006) of TMC278LA, to determine the safety, (local) tolerability and long-term plasma exposure over time of 2 dose regimens of 4 monthly IM doses of a new formulation (F006) of TMC278LA., To determine the safety, (local) tolerability and long-term plasma exposure over time of 1 dose regimen of 4 monthly subcutaneous (SC) doses of a new formulation (F006) of TMC278LA.

Timeline

Start
2008-07
Primary completion
2009-11
Completion
2009-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Rilpivirine Small molecule 300 mg Intramuscular
Subject Rilpivirine Small molecule 600 mg Intramuscular

Indications

No indication recorded.