Rapid Versus Prolonged Inpatient Up-Titration of Captopril

Summary

The primary objective of this study is to establish a safe and effective method of up-titration of captopril for hospital inpatients.

Timeline

Start

2008-08

Primary completion

2009-08

Completion

2009-12

Publications

• Roche SL, Timberlake K, Manlhiot C, Balasingam M, Wilson J, George K, McCrindle BW, Kantor PF. Angiotensin-Converting Enzyme Inhibitor Initiation and Dose Uptitration in Children With Cardiovascular Disease: A Retrospective Review of Standard Clinical Practice and a Prospective Randomized Clinical Trial. J Am Heart Assoc. 2016 May 20;5(5):e003230. doi: 10.1161/JAHA.116.003230.

Drugs

Indications