drugset

drugset / Trial / NCT00745836

Effects of Atorvastatin on Adiponectin Levels and Insulin Sensitivity In Hypercholesterolemic Patients

NCT00745836 ↗

Phase 4 Completed Gachon University Gil Medical Center

Parallel-groupTreatment

Summary

High dose atorvastatin may worsen insulin sensitivity.

Timeline

Start: 2005-01
Primary completion: —
Completion: 2008-08

Publications

Koh KK, Quon MJ, Han SH, Lee Y, Kim SJ, Shin EK. Atorvastatin causes insulin resistance and increases ambient glycemia in hypercholesterolemic patients. J Am Coll Cardiol. 2010 Mar 23;55(12):1209-1216. doi: 10.1016/j.jacc.2009.10.053.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Atorvastatin	Small molecule	10 mg	—
Subject	Atorvastatin	Small molecule	20 mg	—
Subject	Atorvastatin	Small molecule	40 mg	—
Subject	Atorvastatin	Small molecule	80 mg	—

Indications