drugset
drugset / Trial / NCT00745849

Efficacy of Esomeprazole for Non-Allergic Rhinitis: A Double-blind, Placebo Controlled Trial

NCT00745849 ↗

Completed 43 enrolled University of Texas Southwestern Medical Center AstraZeneca · collab
RandomizedCrossoverQuadruple-blindTreatment

Summary

The purpose of this study was to see if high dose esomeprazole (40mg bid) was effective in treating non-allergic rhinitis

Timeline

Start
2005-06
Primary completion
2008-03
Completion
2008-03

Outcome

Missed primary endpoint

registry analysis (superiority test); Esomeprazole Arm vs Placebo Arm; p = 0.45; t-test, 2 sided NCT00745849 ↗

Drugs

EvaluationDrugModalityDoseRoute
Subject Esomeprazole Small molecule 40 mg Oral

Indications

vasomotor rhinitis