Lapatinib and Epirubicin in Treating Patients With Metastatic Breast Cancer. ICORG 06-30

Summary

RATIONALE: Lapatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as epirubicin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving lapatinib together with epirubicin may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of epirubicin when given together with lapatinib in treating patients with metastatic breast cancer.

Timeline

Start

2007-10

Primary completion

2008-11

Completion

2012-03

Drugs

Indications