drugset / Trial / NCT00754858

Belotecan and Cisplatin in Treating Patients With Previously Untreated, Extensive-Stage Small Cell Lung Cancer

NCT00754858

Phase 2 Completed 42 enrolled Yonsei University
NaSingle-groupOpen-labelTreatment

Summary

RATIONALE: Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Belotecan may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving belotecan together with cisplatin may kill more tumor cells. PURPOSE: This phase II trial is studying how well belotecan works when given together with cisplatin in treating patients with previously untreated extensive stage small cell lung cancer.

Timeline

Start
2008-10
Primary completion
2010-05
Completion
2012-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Belotecan Small molecule 0.5 mg/m2 Intravenous
Subject Cisplatin Other / unclassified 60 mg/m2 Intravenous