drugset / Trial / NCT00758641
Platelet Rich Plasma to Treat Plantar Fasciitis
Phase 4
Completed
115 enrolled
Zimmer Biomet
Biomet Nederland BV · collabDiaconessenhuis Leiden Netherlands · collabElisabeth-TweeSteden Ziekenhuis · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Rationale: The standard treatment of chronic plantar fasciitis is corticosteroid injections. Corticosteroid injection give temporarily pain reduction, but no healing. Blood platelets initiate the natural healing rate. GPS ® gives an eightfold concentrate platelets of patients own blood. Injection of these platelets in the tendon might induce a healing rate. Objective: To compare the efficacy of autologous platelet concentrate injections with corticosteroid injection in patients suffering from plantar fasciitis with respect to pain and function.
Timeline
- Start
- 2009-09
- Primary completion
- 2016-01
- Completion
- 2016-01
Publications
- Peerbooms JC, Lodder P, den Oudsten BL, Doorgeest K, Schuller HM, Gosens T. Positive Effect of Platelet-Rich Plasma on Pain in Plantar Fasciitis: A Double-Blind Multicenter Randomized Controlled Trial. Am J Sports Med. 2019 Nov;47(13):3238-3246. doi: 10.1177/0363546519877181. Epub 2019 Oct 11.
- Peerbooms JC, van Laar W, Faber F, Schuller HM, van der Hoeven H, Gosens T. Use of platelet rich plasma to treat plantar fasciitis: design of a multi centre randomized controlled trial. BMC Musculoskelet Disord. 2010 Apr 14;11:69. doi: 10.1186/1471-2474-11-69.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | triamcinolonacetonide | Unknown | 40 mg/ml | — |