drugset / Trial / NCT00758693

Frontline Treatment With Bendamustine in Combination With Rituximab in Adults Age 65 or Older With Chronic Lymphocytic Leukemia (CLL)

NCT00758693 ↗

Non-randomizedSingle-groupOpen-labelTreatment

Summary

Many chemotherapy combinations may be used to treat patients with chronic lymphocytic leukemia (CLL). Although there are many options, a single, best option is not agreed upon by most cancer specialists. Bendamustine, a medicine recently approved for use in the United States, has been used in combination with rituximab in previous studies to treat patients whose CLL has returned after previous standard treatments. The purpose of this study is to determine whether bendamustine with rituximab is effective for the initial treatment of CLL for patients aged 65 and older.

Timeline

Start
2008-10
Primary completion
2010-07
Completion
2010-07

Outcome

Outcome not reported

Stopped (Enrollment): “Funding was withdrawn due to insufficient accrual”

Drugs

EvaluationDrugModalityDoseRoute
Subject Bendamustine Small molecule 100 mg/m2 Intravenous
Subject Rituximab Monoclonal antibody 500 mg/m2 —