drugset / Trial / NCT00758966

Naltrexone SR and Fluoxetine Combination Therapy in Subjects With Obsessive-Compulsive Disorder

NCT00758966

Phase 2 Terminated 8 enrolled Orexigen Therapeutics, Inc
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to determine if the combination of naltrexone SR and fluoxetine is more effective in treating the symptoms of obsessive-compulsive disorder (OCD)than either fluoxetine alone or naltrexone SR alone.

Timeline

Start
2008-09
Primary completion
2008-12
Completion
2008-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Fluoxetine Small molecule 60 mg
Comparator Fluoxetine Small molecule 80 mg
Comparator Naltrexone Small molecule 32 mg
Comparator Naltrexone Small molecule 48 mg