Comparison of Slow and Fast Transition From Stimulants to Atomoxetine in Children and Adolescents With Attention Deficit/Hyperactivity Disorder(ADHD)

Summary

Children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD) who are not tolerating or not responding well to stimulant therapy will be included in this study. Two different strategies for transition from Stimulant to Atomoxetine will be used: Slow (10 weeks) and fast (2 weeks). Changes in ADHD symptoms and tolerability of medication will be compared between the two different switching approaches.

Timeline

Start

2008-09

Primary completion

2010-08

Completion

2010-09

Outcome

Missed primary endpoint

registry Slow Switching Group vs Fast Switching Group; p = 0.692 NCT00760747 ↗

registry Slow Switching Group vs Fast Switching Group; p = 0.927 NCT00760747 ↗

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Atomoxetine	Other / unclassified	1.2 mg/kg	Oral
Subject	Atomoxetine	Other / unclassified	1.8 mg/kg	Oral

Indications