drugset / Trial / NCT00761644

Doxil, Bevacizumab and Temsirolimus Trial

NCT00761644

Phase 1 Completed 200 enrolled M.D. Anderson Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical research study is to learn the highest safe doses of the combination of Doxil (liposomal doxorubicin), Avastin (bevacizumab), and Torisel (Temsirolimus) that can be given to patients with advanced cancer that has spread or is unable to be surgically removed. The safety and effectiveness of this combination of drugs will also be studied.

Timeline

Start
2008-08-21
Primary completion
2019-03-28
Completion
2019-03-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody 5 mg/kg Intravenous
Subject Doxorubicin Other / unclassified 10 mg/m2 Intravenous
Subject Temsirolimus Small molecule 12.5 mg Intravenous

Indications

No indication recorded.