drugset / Trial / NCT00766324
PHA-739358 for Treatment of Hormone Refractory Prostate Cancer
RandomizedParallel-groupOpen-labelTreatment
Summary
To assess the antitumor activity of PHA-739358 administered as IV infusion according to two different dose schedules in metastatic HRPC patients progressing on standard, docetaxel-based 1st-line chemotherapy for HRPC based on PSA response, and to select the best dose schedule for further investigation.
Timeline
- Start
- 2007-09
- Primary completion
- 2011-03
- Completion
- 2011-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | danusertib | Small molecule | — | Intravenous |