A Study for Patient With Chronic Low Back Pain

Summary

The purpose of this study is to determine if duloxetine reduces the severity of chronic low back pain.

Timeline

Start

2008-09

Primary completion

2009-07

Completion

2009-07

Outcome

Met primary endpoint

registry analysis (superiority or other test); Duloxetine vs Placebo; p = 0.001; Mixed Models Analysis NCT00767806 ↗

Publications

• Background Skljarevski V, Zhang S, Desaiah D, Alaka KJ, Palacios S, Miazgowski T, Patrick K. Duloxetine versus placebo in patients with chronic low back pain: a 12-week, fixed-dose, randomized, double-blind trial. J Pain. 2010 Dec;11(12):1282-90. doi: 10.1016/j.jpain.2010.03.002. Epub 2010 May 15.
• Williamson OD, Schroer M, Ruff DD, Ahl J, Margherita A, Sagman D, Wohlreich MM. Onset of response with duloxetine treatment in patients with osteoarthritis knee pain and chronic low back pain: a post hoc analysis of placebo-controlled trials. Clin Ther. 2014 Apr 1;36(4):544-51. doi: 10.1016/j.clinthera.2014.02.009. Epub 2014 Mar 17.

Drugs

Indications