drugset / Trial / NCT00768690
A Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetics of Multiple Doses of ABT-333
RandomizedSingle-groupTriple-blind
Summary
The purpose of this study is to determine multiple dose safety, tolerability and pharmacokinetics of ABT-333 under nonfasting conditions in healthy adult subjects, and to determine the effect of single dose administration of ketoconazole on steady state ABT-333 pharmacokinetics
Timeline
- Start
- 2008-10
- Primary completion
- 2009-02
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ketoconazole | Small molecule | 400 mg | — |
| Subject | dasabuvir | Small molecule | 200 mg | — |
| Subject | dasabuvir | Small molecule | 400 mg | — |
| Subject | dasabuvir | Small molecule | 600 mg | — |
| Subject | dasabuvir | Small molecule | 1000 mg | — |