Evaluation of of a Prefixed 50% N2O- 50%O2 Mixture in Legal Abortion Under Local Analgesia

NCT00769912 ↗

Phase 3 Completed 71 enrolled Assistance Publique Hopitaux De Marseille

RandomizedParallel-groupDouble-blindTreatment

Summary

To evaluate effectiveness of a prefixed 50% N2O- 50%O2 mixture in legal abortion under paracervical block.

Timeline

Start: 2008-10
Primary completion: 2009-02
Completion: 2009-06

Outcome

Missed primary endpoint

paper O(2)/N(2)O did not reduce intraoperative or postoperative pain in elective abortions by vacuum aspiration with paracervical analgesia and intravenous paracetamol PMID 22264664 ↗

Publications

Results Agostini A, Maruani J, Roblin P, Champion J, Cravello L, Gamerre M. A double-blind, randomized controlled trial of the use of a 50:50 mixture of nitrous oxide/oxygen in legal abortions. Contraception. 2012 Jul;86(1):79-83. doi: 10.1016/j.contraception.2011.11.015. Epub 2012 Jan 20.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	50% N2O- 50%O2 mixture	Unknown	—	—

Indications

No indication recorded.