drugset / Trial / NCT00771381
A Study to Determine the Value of 18F-FAZA PET Imaging in Patients With Breast Cancer
NaSingle-groupOpen-labelDiagnostic
Summary
In about half the cases of breast cancer, there is hypoxic (no, or little oxygen) tissue present. Hypoxic cells can be resistant to treatment and may cause increased tumour growth. This study will use 18F-FAZA PET scans before surgery or treatment to assess whether patients have hypoxic tumours. The results will be compared to tissue samples removed during surgery and to the distribution of 18F-FDG.
Timeline
- Start
- 2008-11-28
- Primary completion
- 2019-02-04
- Completion
- 2019-02-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | 18F-FAZA | Diagnostic / imaging agent | 110 mbq | — |
| Subject | 18F-FAZA | Diagnostic / imaging agent | 600 mbq | — |
| Subject | 18F-FDB | Diagnostic / imaging agent | 100 mbq | — |
| Subject | 18F-FDB | Diagnostic / imaging agent | 700 mbq | — |