Using Fludarabine and Melphalan Conditioning Regimen for CLL,Lymphoma,Multiple Myeloma

Phase 2 Completed 38 enrolled Cooperative Study Group A for Hematology

Non-randomizedSingle-groupOpen-labelTreatment

Summary

Allogeneic Non-Myeloablative Stem Cell Transplantation Using Fludarabine and Melphalan Conditioning Regimen for Chronic Lymphocytic Leukemia, Lymphoma, and Multiple Myeloma

Timeline

Start: 2001-07
Primary completion: 2010-09
Completion: 2010-12

Publications

Lee JH, Lee JH, Kim DY, Seol M, Lee YS, Kang YA, Jeon M, Lee KH. A Phase II Trial of Fludarabine/Melphalan 100 Conditioning Therapy Followed by Allogeneic Hematopoietic Cell Transplantation for Patients With Lymphoma. Clin Lymphoma Myeloma Leuk. 2015 Nov;15(11):655-63. doi: 10.1016/j.clml.2015.08.087. Epub 2015 Sep 3.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Fludarabine	Small molecule	30 mg/m2	Intravenous
Comparator	Melphalan	Small molecule	100 mg/m2	Intravenous

Using Fludarabine and Melphalan Conditioning Regimen for CLL,Lymphoma,Multiple Myeloma

Summary

Timeline

Publications

Drugs

Indications