drugset / Trial / NCT00773812
Placebo-Controlled Pilot Trial of Mecamylamine for Treatment of Autism Spectrum Disorders
RandomizedFactorialQuadruple-blindTreatment
Summary
The purpose of this study is to examine the safety and efficacy of mecamylamine for the core symptoms of autism.
Timeline
- Start
- 2007-07
- Primary completion
- 2012-11
- Completion
- 2012-11
Publications
- Results Arnold LE, Aman MG, Hollway J, Hurt E, Bates B, Li X, Farmer C, Anand R, Thompson S, Ramadan Y, Williams C. Placebo-controlled pilot trial of mecamylamine for treatment of autism spectrum disorders. J Child Adolesc Psychopharmacol. 2012 Jun;22(3):198-205. doi: 10.1089/cap.2011.0056. Epub 2012 Apr 26.
- Iffland M, Livingstone N, Jorgensen M, Hazell P, Gillies D. Pharmacological intervention for irritability, aggression, and self-injury in autism spectrum disorder (ASD). Cochrane Database Syst Rev. 2023 Oct 9;10(10):CD011769. doi: 10.1002/14651858.CD011769.pub2.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Mecamylamine | Small molecule | 5 mg | — |