drugset / Trial / NCT00774306
Antiepileptic Drugs and Vascular Risk Markers
Terminated
52 enrolled
Thomas Jefferson University
National Institute of Neurological Disorders and Stroke (NINDS) · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to determine if certain seizure medications raise levels of cholesterol and other blood components which could increase the risk of heart attacks and strokes.
Timeline
- Start
- 2009-04
- Primary completion
- 2012-06
- Completion
- 2012-06
Outcome
Outcome not reported
Stopped: “study no longer consistent with current clinical practice”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Levetiracetam | Other / unclassified | 1000 mg | — |
| Comparator | Levetiracetam | Other / unclassified | 1500 mg | — |
| Comparator | Phenytoin | Unknown | 5 mg/kg | — |
| Comparator | Valproate | Small molecule | 15 mg/kg | — |