drugset / Trial / NCT00777231
Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies
Phase 1/2
Completed
9 enrolled
Talaris Therapeutics Inc.
Duke University · collabHahnemann University Hospital · collabMedical College of Pennsylvania Hospital · collabSt. Christopher's Hospital for Children · collabThe Western Pennsylvania Hospital · collabUniversity of Florida · collab
Non-randomizedSingle-groupOpen-labelTreatment
Summary
The goal of this research study is to establish chimerism and avoid graft-versus-host disease in patients with Hemoglobinopathies to halt disease progression.
Timeline
- Start
- 2005-01
- Primary completion
- 2010-08
- Completion
- 2013-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Enriched Hematopoetic Stem Cell Infusion | Cell therapy | — | — |