Intracoronary Bradykinin Mediated t-PA Release in Heart Transplant Recipients

Summary

Heart transplant recipients do not have nerves to their hearts. This protocol tests the hypothesis that bradykinin mediated t-PA release in the coronary arteries will be reduced in heart transplant recipients compared to healthy subjects. This study will compare heart transplant recipients to healthy controls who are undergoing cardiac cath for standard of care purposes (separate protocol) and compare the coronary arteries to the forearm in transplant recipients (separate protocol) and healthy controls (separate protocol).

Timeline

Start

2008-10

Primary completion

2011-01

Completion

2011-05

Drugs

Indications

No indication recorded.