drugset / Trial / NCT00780442

D-Cycloserine and Cue Exposure in Cocaine-Dependent Individuals

NCT00780442

Phase 2 Completed 27 enrolled Medical University of South Carolina
RandomizedParallel-groupDouble-blindOther

Summary

In summary, this pilot study will explore the use of an innovative pharmacologic approach to the treatment of substance dependence through the facilitation of extinction of response to cocaine-conditioned cues in cocaine-dependent individuals. If DCS proves successful in this preliminary study, a controlled treatment trial will be planned. This novel approach could have implications for the treatment of multiple substance use disorders including methamphetamine, marijuana and opiate dependence.

Timeline

Start
2006-09
Primary completion
2008-07
Completion
2008-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Cycloserine Small molecule 50 mg

Indications