drugset
drugset / Trial / NCT00780481

Characterization of Brachial Arterial t-PA Release, Endothelial Function, Obesity and Inflammation

NCT00780481 ↗

Terminated 13 enrolled Vanderbilt University
NaSingle-groupOpen-labelBasic science

Summary

T-PA release is impaired in obese subjects. In order to have a better mechanistic understanding of t-PA release, we will compare t-PA release to Flow Mediated Vasodilation, Radial Artery Tonometry, and other markers of endothelial function and oxidative stress.

Timeline

Start
2007-01
Primary completion
2011-01
Completion
2011-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Bradykinin Protein / enzyme biologic 0 ng Other
Subject Bradykinin Protein / enzyme biologic 10 ng Other
Subject Bradykinin Protein / enzyme biologic 20 ng Other
Subject Bradykinin Protein / enzyme biologic 40 ng Other

Indications

obesity disorder