drugset / Trial / NCT00782405
Effect of Quetiapine XR on Sleep in Patients With Major Depression, as Compared With Mirtazapine
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to examine the effects of (a) quetiapine XR and (b) mirtazapine on sleep when given as an antidepressant (monotherapy). We hypothesize that (a) quetiapine XR has an immediate and lasting positive effect on sleep in depressed patients which does not differ from the impact of mirtazapine on sleep in this group of patients; (b) in the context of a secondary objective, we expect an antidepressant effect of quetiapine XR which is equivalent to that of mirtazapine.
Timeline
- Start
- 2008-10
- Primary completion
- 2011-04
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Mirtazapine | Other / unclassified | 30 mg | — |
| Comparator | Mirtazapine | Other / unclassified | 45 mg | — |
| Subject | Quetiapine | Small molecule | 150 mg | — |
| Subject | Quetiapine | Small molecule | 300 mg | — |
Indications
No indication recorded.