drugset / Trial / NCT00783731

Low Dose of Midazolam is Superior to Conventional Dose for Rapid Sequence Intubation in Emergency Department (ED)

NCT00783731

Treatment

Summary

Midazolam has been used in rapid sequence intubation for a long time, and the recommended dose is 0.1mg/kg. In some studies, however, the reduced dose has been used with the concern of hemodynamic instability. We would like to investigate that the low dose midazolam could be used rather than the standard recommended dose, and also compare it to the etomidate, recently used sedatives, with respect to the side effects and the easy performance of intubation.

Timeline

Start
2008-10
Primary completion
2010-10
Completion
2011-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Midazolam Small molecule

Indications

No indication recorded.