drugset / Trial / NCT00786643
Study of Gamma Interfereon in Metastatic Colorectal Carcinoma
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to evalute the response and toxicity of metastatic colorectal cancer patients to the regimen of gamma interferon added to bolus and infusional 5-fluorouracil and leucovorin (GFL) with or without bevacizumab.
Timeline
- Start
- 2006-02
- Primary completion
- 2010-03
- Completion
- 2010-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bevacizumab | Monoclonal antibody | 5 mg/kg | — |
| Subject | Interferon gamma-1b | Protein / enzyme biologic | 150 ug/m2 | Subcutaneous |
| Background | Leucovorin | Small molecule | 200 mg/m2 | — |
| Background | fluorouracil | Small molecule | 400 mg/m2 | — |
| Background | fluorouracil | Small molecule | 600 mg/m2 | — |