drugset / Trial / NCT00787605
Aliskiren HCTZ Compared to Amlodipine in Patients With Stage 2 Systolic Hypertension and Diabetes Mellitus
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of the study is to evaluate the blood pressure lowering effect and safety of aliskiren in combination with Hydrochlorothiazide (HCTZ) given to diabetic patients with stage 2 systolic hypertension (mean sitting systolic blood pressure (msSBP) ≥ 160 mm Hg and \< 200 mm Hg).
Timeline
- Start
- 2008-11
- Primary completion
- 2010-01
- Completion
- 2010-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Aliskiren | Small molecule | 300 mg | — |
| Comparator | Amlodipine | Other / unclassified | 10 mg | — |
| Subject | Hydrochlorothiazide | Unknown | 25 mg | — |